Author’s response to reviews Title: Bone pathologic fracture revealing an unusual association : Coexistence of Langerhans cell histiocytosis with Rosai-Dorfman disease Case report and a literature review Authors:
نویسندگان
چکیده
Title: Bone pathologic fracture revealing an unusual association : Coexistence of Langerhans cell histiocytosis with Rosai-Dorfman disease Case report and a literature review Authors: Boubacar Efared ([email protected]) Asmae Mazti ([email protected]) Badarou Chaibou ([email protected]) Gabrielle Atsame-Ebang ([email protected]) Ibrahim Sory Sidibé ([email protected]) Layla Tahiri ([email protected]) Fatimazahra Erregad ([email protected]) Nawal Hammas ([email protected]) Hinde El Fatemi ([email protected]) Laila Chbani ([email protected]) Abdelmajid El Mrini ([email protected]) Version: 1 Date: 11 Feb 2017 Author’s response to reviews: Dear Editor, dear reviewers,
منابع مشابه
Bone pathologic fracture revealing an unusual association: coexistence of Langerhans cell histiocytosis with Rosai-Dorfman disease
BACKGROUND The coexistence of Rosai-Dorfman disease (RDD) with Langerhans cell histiocytosis (LCH) is very rare, as to date only 17 cases have been reported in the english literature. The pathophysiology of this uncommon co-occurrence still remains enigmatic and a subject of various speculations. CASE PRESENTATION We report a case of a 30-year-old female patient who presented with a pathologi...
متن کاملRosai-Dorfman Disease: A Case Report and Literature Review
Rosai-Dorfman disease or sinus histiocytosis with massive lymphadenopathy is a rare disorder that typically manifests as lymphadenopathy and systemic symptoms whose etiology remains poorly elucidated. The diagnosis is based on immunohistochemistry. Its treatment is poorly defined but the prognosis is usually favorable. Here we report a 14 year old boy who presented with massive bilateral cervi...
متن کاملCombined Cutaneous Rosai-Dorfman Disease and Localized Cutaneous Langerhans Cell Histiocytosis Within a Single Subcutaneous Nodule
Rosai-Dorfman disease (RDD) is a reactive multisystem histiocytosis that typically presents with cervical lymphadenopathy and systemic symptoms. Cutaneous involvement occurs in approximately 10% of cases, and 3% of cases are limited to the skin without nodal or other extranodal involvement. Langerhans cell histiocytosis (LCH) is a clonal histiocytosis with a wide spectrum of presentations rangi...
متن کاملRosai-Dorfman disease and juvenile xanthogranuloma in a Thai boy: report of a case.
A 3-year-old Thai boy suffered from two histiocytoses, Rosai-Dorfman disease (RDD) and juvenile xanthogranuloma (JXG). The patient first presented with massive cervical lymphadenopathy at the age of one year. Biopsy revealed typical RDD; abnormally large CD68- and S-100 protein-positive histiocytes with occasional emperipolesis filled up the sinuses. Two years later, he developed polyuria and p...
متن کاملRosai-Dorfman disease of vertebra: Case report and literature review.
Rosai-Dorfman disease is a rare benign histiocytic disorder that arises predominantly in lymph nodes with fever and malaise, but can affect various organs, with or without lymphadenopathy. Solitary extranodal skeletal lesions are extremely rare. Herein, we describe a case of isolated disease of thoracic spine, with vertebral body fracture. A 14-year-old girl presented with cervical back pain fo...
متن کامل